Which thrombolytic agent can be given in a single bolus injection? What are its advantages?

TENECTEPLASE

Advantages
Single IV bolus dose
Fibrin specific
Weight-adjusted dosing
Less bleeding chances
Long half-life
PAI-resistant
Best suited for pre-hospital use

How sensitive is ECG for diagnosis of MI?

Single 12 lead ECG is 50-70% sensitive.
Serial ECGs >80% sensitive.

Characteristics of normal sinus rhythm?

P wave of sinus origin
Constant PR interval
Rate between 60-100/min
Constant P wave configuration
Constant PP or RR INTERVAL

What are the common sites of cardiac calcification?

 a LV apex

b LV aneurysm

c Aortic valve

d Mitral valve

e PDA calcification

f Pericardium

g Coronaries

i Conduction system

Name the disease in which grotesque facial features are seen? Enumerate the cardiac conditions associtaed

• HURLER'S SYNDROME
• Grotesque facial features - prominent supraorbital ridge, depressed nasal bridge, thick lips, corneal clouding, peg shaped teeth
• CARDIAC CONDITIONS ASSOCIATED ARE

• CAD
• AR
• HOCM
• Mitral annulus calcification (MR)

What are Brushfield's spots?

• Grayish white spots at the periphery of the iris
• It is more clearly seen in dark pigmented iris
• Seen in DOWN'S SYNDROME

 

What are the causes of thrombosis in situ in coronary artery?

• TTP
• Polycythemia vera
• Sickle cell anemia
• Primary thrombocytosis